Found 11 matching trials
A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants PHASE1 This study will look at how a drug (tucatinib) leaves the body and what hap...
Show More Location
Covance Clinical Research Unit
Learn More & Join Trial
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer PHASE2 The purpose of this study is to further advance the ability to practice per...
Show More Location
University of Alabama at Birmingham
Learn More & Join Trial
Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease PHASE2 The goal of this clinical trial is to evaluate the efficacy of tucatinib an...
Show More Location
Institut Bergonié
Learn More & Join Trial
Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study PHASE2 The proposed study will evaluate the safety and efficacy of XRT followed by...
Show More Location
The Ottawa Hospital
Learn More & Join Trial
A Safety, Tolerability, and Pharmacokinetic Study of Tucatinib in Healthy Japanese and Caucasian Subjects PHASE1 This study is being done to compare the pharmacokinetics (PK) and safety/to...
Show More Location
PAREXEL International, Early Phase Clinical Unit - Los Angeles
Learn More & Join Trial
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer PHASE2 The purpose of this study is to test the safety and effectiveness of a sequ...
Show More Location
Dana-Farber Cancer Institute
Learn More & Join Trial
Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002) PHASE1 The primary purpose of this study is to characterize the safety and tolerab...
Show More Status
Active Not Recruiting
Location
Harbin Medical University Cancer Hospital
Learn More & Join Trial
Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients PHASE2 The aims of this study are to evaluate if an intensified adjuvant treatment...
Show More Location
Fondazione Casa Sollievo della Sofferenza
Learn More & Join Trial
TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases PHASE1 This is a single arm, open label trial to assess the safety and efficacy of...
Show More Location
Cedars-Sinai Medical Center
Learn More & Join Trial
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers PHASE2 This trial studies tucatinib to find out if it is safe when given with tras...
Show More Status
Active Not Recruiting
Location
Mayo Clinic Hospital
Learn More & Join Trial